The life of Lizzie Velasquez, now 26, changed for ever after she stumbled across a YouTube video labelled 'The world's ugliest woman.'
Lizzie, who was just 17 at the time, was horrified to find that the girl in the clip was her.
The vicious footage was watched 4 million times online, with many leaving disgusting comments about Lizzie, including suggestions that she should have been killed at birth.
"I was shocked," she said, "but it wasn't until I started to read the comments that my stomach really sank."
One of the comments read: "Why would her parents keep her?!" while another said "kill it with fire," the BBC reports.
Lizzie said she was unable to bring herself to read some of the comments.
"I cried for many nights - as a teenager I thought my life was over," said.
Lizzie decided to fight back by starting her own YouTube channel revealing the person behind the "World's Ugliest Woman" video.
There are currently around 240,000 subscribers to her channel.
Lizzie says she makes others who have been bullied for the way they look feel able to seek help, or stand up to the bullies.
She also works with Tina Meier whose daughter Megan killed herself after being bullied online.
Lizzie was used to be bullied for the way she looks after being born with the rare conditions - Marfan and lipodystrophy.
She is 5ft 2in and weighs about 60lbs (27kg) - blind in her right eye and has partial sight in the other.
Lizzie has been in and out of hospital for surgery many times.
And now her life has been touched upon in a new film which is due to premier at the South by Southwest festival in Austin, Texas today.
Sara Hirsch Bordo, the director of the film - "The Lizzie Project" - said: "Her experience of triumphing adversity and making it to the other side of a painful experience is universal," she says.